Nanoemulsion gels have emerged as one of the most interesting topical delivery system as it has dual release control\r\nsystem i.e. gel and emulsion. The major objective behind this formulation is delivery of hydrophobic drugs to systemic\r\ncirculation via skin. Nanotechnology with the use of nano sized particles has largely succeeded in overcoming skin barriers and\r\nhence nano sized emulsion easily penetrate the pores of the skin and reach the systemic circulation thus getting channelized for\r\neffective deliver. Nanoemulsion gel formulation provides better application property and stability in comparison to cream and\r\nointment. Topical gel drug administration is a localized drug delivery system anywhere in the body through ophthalmic, rectal,\r\nvaginal and skin as topical routes. Skin is one of the most extensive and readily accessible organs on human body for topical\r\nadministration and is main route of topical drug delivery system. Topical application of drugs offers potential advantages of\r\ndelivering the drug directly to the site of action and acting for an extended period of time. Topical Nanoemulsion gels are\r\nintended for skin application or to certain mucosal surfaces for local action or percutaneous penetration of medicament or for\r\ntheir emollient or protective action. Nanoemulsion gels are evaluated by following parameters such as pH, homogeneity,\r\ngrittiness, drug content, viscosity, spreadability, extrudability, skin irritation studies, in-vitro release, stability studies.
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