Next generation in-to-out-of body biomedical applications have adopted optical wireless communications (OWCs). However, by delving into the published literature, a gap is recognized in modeling the in-to-out-of channel, since most published contributions neglect the particularities of different types of tissues. In this paper, we present a novel pathloss and scattering models for in-toout- of OWC links. Specifically, we derive extract analytical expressions that accurately describe the absorption of the five main tissues’ constituents, namely fat, water, melanin, and oxygenated and deoxygenated blood. Moreover, we formulate a model for the calculation of the absorption coefficient of any generic biological tissue. Next, by incorporating the impact of scattering in the aforementioned model, we formulate the complete pathloss model. The developed model is verified by means of comparisons between the estimated pathloss and experimental measurements from independent research works. Finally, we illustrate the accuracy of the proposed model in estimating the optical properties of any generic tissue based on its constitution. The extracted channel model is expected to enable link budget analysis, performance analysis, and theoretical framework development, which will boost the design of optimized communication protocols for a plethora of biomedical applications.
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