Jatropha curcus Linn. seeds were extracted using water to obtain aqueous extracts. This extract was evaluated for anticataleptic activity using clonidine induced and haloperidol-induced catalepsy models at the dose of 50 mg/kg, (i.p.). The aqueous extracts (50 mg/kg, i.p.) of the plant significantly inhibited clonidine-induced catalepsy but not inhibited haloperidolinduced catalepsy. The HIC model was used to assess anticataleptic drugs. Inhibition of cataleptic score predicts activity of drug against parkinson's disease. Thus polar constituents of the plant can be used as anticataleptic.
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