The Sphaeranthus indicus Linn. (Asteraceae) a traditional Indian medicinal plant is commonly used to nourish and improve the stomach conditions. This study was designed to evaluate the anti ulcer potential of Sphaeranthus indicus. The aerial part was successively extracted with solvents of varying polarities, which serve as test extracts. Anti ulcer effect was checked in albino rats using pyloric ligation induced and aspirin induced ulcer model .Ranitidine at a dose of 25mg/kg was used as standard drug for the gastric ulcer model. The gastric content was collected and volume was measured. The ulceration index was determined by examining the inner lining of each stomach. Further more the effect was assed by free acidity, total acidity and ulcer index. The Ethanol extract and Aqueous extract was found to posses the most effective anti ulcer activity. This proves the traditional claim of the plant as anti ulcer drug.
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