Introduction: The Cussons Baby Sensicare Range is a newly developed set of\nproducts specially formulated for newborn, sensitive and eczema prone skin.\nAs such, these products need to be tested to evaluate their skin irritation and\nsensitization potential before use. The products were evaluated with two separate\ntests. The first test was conducted in a single-center, within-subject\ncomparison using assessor-blind, randomised human skin irritation patch\ntest (48 hour/96 hour exposure) and conducted on healthy adults with sensitive,\natopic skin. The second test was conducted in a single-center, controlled\n(sterile water), within subject using human repeat-insult patch tests (HRIPTs)\nand conducted on healthy female Indonesian and Asian adult female subjects,\nwith sensitive skin. The sensitization potential of each product was determined\nfrom International Contact Dermatitis Research Group (ICDRG)\nscores at 30 minutes, 24 hours, 48 hours and 72 hours after patch removal.\nSkin irritation tests show that all products were significantly lower than the\npositive control sodium lauryl sulphate (SLS) (p < 0.05) but not significantly\ndifferent to the negative control (sterile water) in terms of irritation scores at\nthe respective time points. HRIPTs results show that Cussons Baby Sensicare\nRange was non-sensitizing. As such, it can be concluded that the Cussons\nBaby Sensicare Range tested is well tolerated on skin and has low skin irritation\nand sensitization potential. Thus, they can be considered hypoallergenic \non sensitive skin and suitable for eczema prone skin.
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