Background. Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. Psychological stress\r\ncan exacerbate the disease. This study sought to investigate the depression and anxiety disorders among patients with psoriasis\r\nand control group. Method. In this hospital-based case-control study, One hundred patients with psoriasis (case) referred to the\r\ndermatology department and 100 patients with otolaryngology problems and dermatological healthy volunteers (control) who\r\nreferred to the Otolaryngology Department of Bouali SinaHospital in Sari, Iran, in 2007 were studied. Demographic characteristics\r\nwere recorded. Beck Depression Inventory and Spielberger State-Trait Anxiety Scale I-II were administered to the patients in both\r\ngroups. Data were analyzed using SPSS statistical software and descriptive statistical tests. Results. From One-hundred patients\r\nin each group, 44 (45%) were men. Depression score was 67% and 12% in psoriatic patients and control, respectively. The\r\nBeck depression scores of patients with psoriasis were significantly higher than scores of the control group (P < 0.05). Based\r\non Spielberger State-Trait Anxiety Scale, anxiety was found in 45% of patients in case group and 18% of controls. Conclusion. The\r\nresults revealed that psoriatic patients reported significantly higher degrees of depression and anxiety than controls. In addition,\r\npsoriatic women were more depressed than psoriatic men.
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