A new naproxen amide prodrug was synthesized and spectrally characterized and a simple, precise, and accurate stabilityindicating\nRP-HPLC method was developed and validated for determination and chemical hydrolysis study of the prodrug. Forced\ndegradation studies were conducted as per the International Conference on Harmonization (ICH) guidelines to establish the\nstability-indicating power of the method. Separations were performed on a C18 column (150 Ã?â?? 4.6mm i.d., 5
Loading....