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Inventi Impact: Pharm Analysis & Quality Assurance

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  • Inventi:ppaqa/30031/19
    Comparison of Retention Behavior Between Supercritical Fluid Chromatography and Normal-Phase High-Performance Liquid Chromatography with Various Stationary Phases
    Research 2019 : October - December
    Tsunehisa Hirose, Daniel Keck, Yoshihiro Izumi, Takeshi Bamba

    The retention behavior of a wide variety of stationary phases was compared in supercritical\nfluid chromatography (SFC) and normal-phase high-performance liquid chromatography (NP-HPLC).\nWe also attempted to elucidate the retention behavior in SFC by investigating the selectivity of the\ndifferent stationary phases. SFC separation conditions with polar stationary phases, such as silica gel\n(SL) and diol (Diol) phases, operate via adsorptions that include hydrophilic and ionic interactions\nsimilar to those in NP-HPLC. Moreover, non-polar stationary phases, such as pentabromophenyl\n(PBr), pyrenylethyl (PYE), and octadecyl (C18), could be used despite the non-polar mobile phase\nconditions, because the dispersion�������..

    How to Cite this Article
    Attribution/ CC Compliant Citation: Hirose, Tsunehisa, et al. \"Comparison of Retention Behavior between Supercritical Fluid Chromatography and Normal-Phase High-Performance Liquid Chromatography with Various Stationary Phases.\" Molecules 24.13 (2019): 2425.\nhttps://doi:10.3390/molecules24132425\nhttp://creativecommons.org/licenses/by/4.0/\n\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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