An innovative chromatographic analysis was developed for the determination of\nmoniliformin (MON). Because of its ionic nature, MON is weakly retained in reversed-phase\nchromatography and the separation may be tricky. Nevertheless, this technique is normally used\neither with the formation of ion pairs or employing specific RP columns for polar compounds, or\ncombining anion exchange and hydrophobic interactions. Hydrophilic interaction chromatography\n(HILIC) was also used, but a non-negligible peak tailing was observed. Besides its ionic nature, MON\nis a di-ketone and di-ketones, mainly Beta-di-ketones, can easily form complexes with lanthanide ions.\nThen, in this work the addition of lanthanide ions to the mobile phase was investigated, aiming at\nimproving peak shape and MON separation������.
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