Analysis of beta blockers in formulated and unformulated samples demand a highly specific and rapid method as many beta blockers have serious stability problems. HPLC techniques can provide a valuable tool for generating highly pure preparations for characterizing and identification of the beta blockers and its combined dosage form. In the present review article, column and mobile phase conditions for the various Beta Blockers viz. Atenolol, Bisoprolol, Carvedilol, Metoprolol, Nebivolol, Propranolol, etc. have been presented. A brief discussion on chemical structure, spectrum of activity and action mechanism of each beta blocker has also been given.
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