Background. To evaluate the efficacy of intravitreal bevacizumab (IVB) injection with or without macular laser photocoagulation\n(MLP) for recurrent or persistent macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods. Thirty-four\neyes underwent IVB injection for ME secondary to BRVO as a primary treatment. Twenty of the 34 eyes experienced recurrent\nor persistent ME after the first IVB. Nine of the 20 eyes (Group 1) were retreated with IVB combined with MLP.The remaining 11\neyes (Group 2) were retreated with IVB alone. Results. In Group 1, the postoperative best corrected visual acuity (BCVA) improved\ncompared with the preoperative value at all follow-up visits, although no statistically significant improvement was observed at 6\nmonths. In contrast, BCVA significantly improved from 0.53 to 0.40 at 6 months (P < 0.05) in Group 2. Conclusion. Combined\ntherapy tended to have a smaller effect on visual acuity compared with IVB monotherapy.
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