Background. To compare the efficacy of needle revision with 5-fluorouracil (5-FU) and mitomycin C (MMC) on dysfunctional\nfiltration blebs shortly after trabeculectomy. Methods. It is a prospective randomized study comparing needle revision augmented\nwith MMC or 5-FU for failed trabeculectomy blebs. Results. To date 71 patients (75 eyes) have been enrolled, 40 eyes in the MMC\ngroup and 35 in the 5-FU group. 68 patients (72 eyes) have completed 12-month follow-up, 38 eyes in theMMC group and 34 in the\n5-FU group. The mean IOP before and that after needle revision in the MMC group were 26.5 �± 4.3mmHg and 11.3 �± 3.4mmHg,\nrespectively (
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