Background: Glaucoma combined with an extremely shallow anterior chamber and cataracts remains as a\ncomplex condition to deal with. And the emergence of microincision vitrectomy surgery (MIVS) system may\nprovide an ideal option for the treatment of that. We report a clinical study of surgical outcomes of 23-gauge\ntransconjunctival pars plana vitrectomy (PPV) combined with lensectomy in the treatment of glaucomatous eyes\nwith extremely shallow anterior chamber and cataract.\nMethods: Prospective, nonrandomized and noncomparative case series study. Consecutive patients with secondary\nglaucoma, extremely shallow anterior chamber and cataract were recruited to have combined surgeries of 23-gauge\ntransconjunctival pars plana vitrectomy and lensectomy. The main outcomes were best corrected visual acuity (BCVA),\nintraocular pressure (IOP), anterior chamber depth (ACD), number of anti-glaucoma medications and surgeryassociated\ncomplications.\nResults: Seventeen consecutive patients with secondary glaucoma, extremely shallow anterior chamber and cataract\nwere recruited. The mean follow-up was 21.2 �± 8.8 months. Postoperatively, there was no significant improvement of\nBCVA (P = 0.25). The mean intraocular (IOP) decreased significantly from 43.14 �± 6.53 mmHg to 17.29 �± 1.80 mmHg\n(P < 0.001), and the mean depth of anterior chamber increased significantly from 0.507 �± 0.212 mm to 3.080 �±\n0.313 mm (P < 0.001). The mean number of anti-glaucoma medications decreased from 4.1 �± 0.8 to 0.6 �± 0.8\n(P < 0.001). No severe vision-threatening intra- or post-operative complications occurred.\nConclusions: Glaucoma with an extremely shallow anterior chamber and cataract can be managed well with the\ncombined surgeries of 23-gauge pars plana vitrectomy and lensectomy. The surgical procedure is an effective and\nsafe method to resolve the pupillary block and deepen the anterior chamber.
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