Background: Icare PRO (ICP) is a new Rebound tonometer that is able to measure intraocular pressure (IOP) in\r\nboth sitting and reclining positions. In this study, the gold standard Goldmann tonometer (GAT) was compared to\r\nICP and Tono-Pen AVIA (TPA). Hypothesis was that repeatability of GAT is superior to ICP and TPA.\r\nMethods: 36 eyes of 36 healthy caucasian individuals, 13 male and 26 females, 17 right and 19 left eyes have\r\nbeen included in this prospective, randomized, cross-sectional study. The study was conducted at a single site\r\n(Dept. of Ophthalmology, UniversityHospital Zurich, Switzerland). Primary outcome measures were Intraclass\r\ncorrelation coefficients (ICC) and coefficients of variation (COV) and test-retest repeatability as visualized by\r\nBland-Altman analysis. Secondary outcome measures were IOP in sitting (GAT, ICP and TPA) and in reclining\r\n(ICP and TPA) position.\r\nResults: Mean IOP measured by GAT was 14.9�±3.5 mmHg. Mean IOP measured by ICP was 15.6�±3.1 mmHg (with\r\nTPA 14.8�±2.7 mmHg) in sitting and 16.5�±3.5 mmHg (with TPA 17.0�±3.0 mmHg) in reclining positions. COVs ranged\r\nfrom 2.9% (GAT) to 6.9% (ICP reclining) and ICCs from 0.819 (ICP reclining) to 0.972 (GAT).\r\nConclusions: Repeatability is good with all three devices. GAT has higher repeatability compared to the two\r\ntested hand-held devices with lowest COVs and highest ICCs. IOP was higher in the reclining compared to the\r\nsitting position.
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