Celiac disease (CD) is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals.\nWorldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with\ninfertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac\nwomen aged 15ââ?¬â??49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basilicata\n(Italy). Moreover, we selected hospital discharge records (HDRs) of celiac women and women with an exemption for CD, and\nmatched the lists with HDRs for reproductive disorders. In the surveys we included 91 celiac women; 61.5% of them reported\nmenstrual cycle disorders. 47/91 reported at least one pregnancy and 70.2% of them reported problems during pregnancy. From\nthe HDRs and the registry of exemption, we selected 4,070 women with CD; the proportion of women hospitalized for infertility\nwas higher among celiac women than among resident women in childbearing age (1.2% versus 0.2%). Our findings highlight a\nhigher prevalence of reproductive disorders among celiac women than in the general population suggesting that clinicians might\nconsider testing for CD women presenting with pregnancy disorders or infertility.
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