PCOS (Poly Cystic Ovarian Syndrome) is the most common endocrine disorder in females with high prevalence. The\r\nsyndrome was originally described by Stein and Levanthal as Stein and Levanthal syndrome in 1935 as a triad consisting of\r\namenorrhea, hirsutism and obesity in women who had multiple cysts on their ovaries. Over the last decade or so the\r\nunderstanding of this syndrome has changed and the emphasis is often on the long term consequences that may occur.\r\nWorldwide PCOS is a common endocrine disorder where there is an imbalance in the hormones produced in women�s body with\r\nan incidence of 5-10%. The condition causes a wide range of problems ranging from acne to infertility. PCOS is associated with\r\nvarious risk factors like obesity, hereditary factors, sedentary life style, Hormonal imbalance, Family history of Diabetes. Medical\r\nmanagement of PCOS is aimed at the treatment of metabolic derangements, anovulation, hirsutism and menstrual irregularity.\r\nPCOS clinical features include oligomennorgea, infertility, dyslipidaemia, obesity, hyperandrogenism etc. Although there are\r\nmany diagnostic procedures for PCOS, the most efficacious procedure was ultrasound scanning. The use of insulin-sensitizing\r\ndrugs like metformin to improve insulin sensitivity is associated with a reduction in circulating androgen levels, as well as\r\nimprovement in both the ovulation rate and glucose tolerance. First-line medical therapy usually consists of an oral\r\ncontraceptive to induce regular menses. The contraceptive not only inhibits ovarian androgen production but also increases sex\r\nhormone-binding globulin (SHBG) production. First-line treatment for ovulation induction when fertility is desired is\r\nclomiphene citrate. Comprehensive evidence-based guidelines are needed to aid early diagnosis, appropriate investigation,\r\nregular screening and treatment of this common condition. This review focuses on overview of disease, etiology, clinical features\r\nand treatment of PCOS.
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