Introduction. The prognostic value of age, physical status, and duration of surgery on perioperative course has been extensively\nstudied. However, the impact of deep hypnotic time (time when Bispectral Index values are less than 40) has not been well\nevaluated. Methods.We designed an observational study to clarify the relative influence of deep hypnotic time (DHT) on outcome.\nEligible participants were mentally stable patients over 18 years old scheduled for elective major abdominal surgery. In total,\n248 patients enrolled. Data were analyzed using Fisherââ?¬â?¢s exact test and multiple logistic regression. Results. Five variables (DHT,\nhypotension, age, comorbidity, and duration of surgery) showed statistically significant association with complications, when\nexamined independently. However, when all variables were examined together in a multiple logistic regression model, age and\ncomorbidity were no longer associated with outcome. DHT, hypotension, and duration of surgery were significant predictors of\nââ?¬Å?complications,ââ?¬Â and ââ?¬Å?hypotensionââ?¬Â was a significant predictor of prolonged hospital stay (P < 0.001). Conclusion. Deep hypnotic\ntime emerged as a new factor associated with outcome, and its impact compared to other factors such as age, surgery duration,\nhypotension, and comorbidity is redefined.Monitoring and managing depth of anesthesia during surgery are important and should\nbe part of careful operation planning
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