Objective: To compare P6 acupuncture plus ondansetron with either ondansetron\nor P6 acupuncture in the prevention of postoperative nausea and\nvomiting (PONV) in patients submitted to spinal anesthesia. Methods: A\nrandomized controlled trial was performed with 90 patients undergoing orthopedic\nsurgery under spinal anesthesia with bupivacaine, 15 to 17.5 mg, and\nmorphine, 100 �¼g. They were assigned to one of the three groups: Group Ondansetron\n(n = 30), patients were given ondansetron, 8 mg intravenously, before\nspinal block was performed; Group P6 acupuncture (n = 30), patients\nwere subjected to bilateral electrical stimulation of P6 acupoint for 30 minutes\nbefore anesthesia; and Group P6 acupuncture plus ondansetron (n = 30), the\nexact combination of the groups Ondansetron and P6 acupuncture. Results:\nIn the post anesthesia care unit, the incidence of nausea and vomiting ranged\nfrom 13.3% to 26.7% and from 6.7% to 13.3%, respectively, with no significant\ndifferences among groups (p > 0.05). Ondansetron group had the highest incidence\nof nausea (73.3%) (p < 0.001) and vomiting (43.3%) (p < 0.001) at the\nward from 0 to 24 hours, followed by P6 acupuncture (33.3% and 26.7%) and\nP6 acupuncture plus ondansetron groups (16.0% and 0%). Conclusion:\nPreoperative stimulation of P6 acupoint in combination with ondansetron has\nhigher efficacy than either P6 acupoint stimulation or the administration of ondansetron on the prevention of PONV in patients submitted to bupivacaine-\nmorphine spinal anesthesia.
Loading....