Background: Ultrasound-guided for regional anesthesia offers many potential\nbenefits in the emergency setting. Analgesia can be explicitly targeted to\nthe region of pain and provide relief for many hours and decrease needing to\nthe large volume of local anesthetic. The aim of the work: Comparing the efficacy\nof dexmedetomidine when used as an adjuvant to bupivacaine in supraclavicular\nbrachial plexus blocks on the onset of sensory, motor blockade\nand postoperative analgesia. Patients and methods: This prospective, randomized,\nsingle-blind clinical study conducted on 60 patients underwent upper\nlimb surgery done by ultrasound-guided supraclavicular brachial plexus\nblock; these patients allocated into two equal groups: Group I (control) received\n20 ccs (19 cc bupivacaine 0.5% + 1 cc saline), Group II received 20 cc\n(19 cc bupivacaine 0.5% + 1 cc volume of Dexmedetomidine 1 ug/kg). Results:\nDemographic data and surgical characteristics were comparable in both\ngroups. The onset times for sensory and motor blocks were significantly\nshorter in Group II than Group I (P < 0.001), while the duration of blocks\nwas considerably longer (P < 0.001) in Group II. Except for the first recordings\n(at 0, 5, and 10 min), heart rate levels in Group II were significantly lower\n(P < 0.001). MBP levels in Group II at 15, 30, 45, 60, 90 and 120 min were\nsignificantly lower than in Group I (P < 0.001). The duration of analgesia\n(DOA) was significantly longer in Group II than Group I (P < 0.001). As regards\nto the visual Analouge score, there is a highly significant difference at 6\nhours, 8 hours and 10 hours in Group II than Group I. Conclusion: We\nrecommend adding Dexmedetomidine to local anesthetics in peripheral nerve\nblocks to take advantage of the prolonged time of both sensory and motor\nblocks and prolonged postoperative analgesia.
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