Oral squamous cell carcinoma (OSCC) is usually preceded by detectable mucosal changes, as leukoplakias and erythroplakia.\nHistologically, these lesions can range from hyperkeratosis and acanthosis to epithelial dysplasia and even OSCC. The aim of\nthis study was to investigate the proliferative activity, using AgNORs quantification proteins, in low- and high-risk oral epithelial\ndysplasia, OSCC, and nondysplastic epithelium (inflammatory fibrous hyperplasia). The sample was divided into 4 groups: G1:\n10 cases of inflammatory fibrous hyperplasia (IFH), G2: 11 cases of low-risk epithelial dysplasia (LD), G3: 10 cases of high-risk\nepithelial dysplasia (HD), and G4: 11 cases of OSCC. The quantitative analysis was performed using an image processing software in\nphotomicrographs at 1000x magnification.The one-way ANOVA was used for comparison of the mean AgNORs counts between\nthe study groups. The mean AgNORs count was significantly higher (
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