Background: To investigate clinical features of infectious endophthalmitis over five years in a South Korean\npopulation.\nMethods: Medical records of consecutive patients diagnosed with infectious endophthalmitis at eight institutions\nlocated in Gyeongsangnam-do and Pusan city between January 1, 2004 and July 31, 2010 were reviewed.\nResults: A total of 197 patients were diagnosed and treated. An average of 30.0 infectious endophthalmitis per\nyear was developed. The annual incidence rate of postoperative endophthalmitis during 2006 ~ 2009 was 0.037%.\nThe ratios of male to female and right to left were 50.2%: 49.8 % and 54.8%: 43.2%, respectively. Eighth decade\nand spring were the peak age (36.6%) and season (32.0%) to develop the infectious endophthalmitis. The most\ncommon past history in systemic disease was hypertension (40.4%), followed by diabetes (23.4%). Cataract\noperation (60.4%) was the most common cause, among which most of them was uneventful phacoemulsification\n(95.9%). Corneal laceration (51.6%) and liver abscess (42.9%) were the most common causes of traumatic and\nendogenous endophthalmitis, respectively. The percentages of patients with initial and final visual acuity less than\ncounting fingers were 62.6% and 35.2%, respectively. Treatment with vitrectomy with or without intravitreal\nantibiotics injection was administered to 72.6% of patients, while 17.3% received intravitreal antibiotics only.\nConclusions: Our study revealed that the development of infectious endophthalmitis was related with seasonal\nvariation and increased during our study period. Pars plana vitrectomy was preferred for the treatment of infectious\nendophthalmitis in South Korea.
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