Introduction: The literature on surgical salvage, i.e. lung resections in patients who develop a local recurrence\nfollowing stereotactic ablative radiotherapy (SABR), is limited. We describe our experience with salvage surgery in\nnine patients who developed a local recurrence following SABR for early stage non-small cell lung cancer (NSCLC).\nMethods: Patients who underwent surgical salvage for a local recurrence following SABR for NSCLC were identified\nfrom two Dutch institutional databases. Complications were scored using the Dindo-Clavien-classification.\nResults: Nine patients who underwent surgery for a local recurrence were identified. Median time to local\nrecurrence was 22 months. Recurrences were diagnosed with CT- and/or 18FDG-PET-imaging, with four patients\nalso having a pre-surgical pathological diagnosis. Extensive adhesions were observed during two resections,\nrequiring conversion from a thoracoscopic procedure to thoracotomy during one of these procedures. Three\npatients experienced complications post-surgery; grade 2 (N = 2) and grade 3a (N = 1), respectively. All resection\nspecimens showed viable tumor cells. Median length of hospital stay was 8 days (range 5ââ?¬â??15 days) and 30-day\nmortality was 0 %. Lymph node dissection revealed mediastinal metastases in 3 patients, all of whom received\nadjuvant therapy.\nConclusions: Our experience with nine surgical procedures for local recurrences post-SABR revealed two grade IIIa\ncomplications, and a 30-day mortality of 0 %, suggesting that salvage surgery can be safely performed after SABR.
Loading....