Background: Diffusion-weighted imaging (DWI) and ultrasound are commonly used methods to examine thyroid\nnodules, but their comparative value is rarely studied. We evaluated the utility of DWI and ultrasound in\ndifferentiating benign and malignant thyroid nodules.\nMethods: A total of 100 patients with 137 nodules who underwent both DWI and ultrasound before operation\nwere enrolled. The T1 and T2 signal intensity ratio (SIR) of each thyroid nodule was calculated by measuring the\nmean signal intensity divided by that of paraspinal muscle. The apparent diffusion coefficient (ADC) value and the\nSIR of benign and malignant thyroid nodules were analyzed by two-sample independent t tests. The sensitivity,\nspecificity, and accuracy of DWI and ultrasound were compared with chi-square tests.\nResults: There was no significant difference in the SIR between benign and malignant thyroid nodules. The ADC\nvalue was significantly different. ............................
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