Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract. The major cause of GIST is the\npresence of an abnormal form of tyrosine protein kinase (KIT) protein also known as CD117, which causes uncontrollable\ngrowth of the gastrointestinal cells. Most studies report incidences between 10 and 15 cases of GISTs per million. Metastases to\nthe liver and peritoneum are the most frequent. We report a case of advanced GIST with a liver metastasis infiltrating the\ninferior vena cava (IVC) and extending to the right atrium in the form of a large, floating, isolated intracardiac liver metastasis\nwith diastolic prolapsing through the tricuspid valve. This is a very rare manifestation. One week after heart surgery and\nremoval of a 5* 6cm tumor mass from the right atrium and the IVC, echocardiography depicted an early recurrence.
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