Background. The correlation between Helicobacter pylori (H. pylori) and gastroesophageal reflux disease (GERD) is complex. Some\nstudies showed a protective role of H. pylori infection against GERD. This study was aimed at assessing the role of H. pylori infection\nin GERD utilizing a large cohort of patients diagnosed with GERD. Methods and Materials. All patients who underwent gastroscopy\nfor an indication of GERD during the study period between 2015 and 2017 at the EMMS Nazareth Hospital were considered eligible\nfor the study and therefore were included. H. pylori infection was determined by the rapid urease test or histology. Severity of\nesophagitis was assessed using the Los Angeles classification. Univariate analysis was performed to figure out differences\nbetween patients according to H. pylori infection status. Multivariate regression analysis was conducted to illustrate the\npredictors of positivity for H. pylori infection.......................
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