Background/Aim. Endoscopic balloon dilation (EBD) has been effective for small-bowel strictures in patients with Crohnâ??s disease\n(CD). However, its efficacy and indication for small-bowel strictures in non-CD patients have not been established. This study\nevaluated the clinical efficacy and safety of EBD for small-bowel strictures in non-CD patients compared with CD patients.\nMethods. Ninety-eight consecutive patients (mean age, 53 years; average observation period, 45 months) with small-bowel\nstrictures diagnosed by double-balloon endoscopy were retrospectively evaluated at Hiroshima University Hospital from\nAugust 2003 to April 2017. The average number of procedures, short-term and long-term EBD success rates, and safety\nprofiles between the non-CD and CD groups were examined. Results. Surgery was selected as the initial treatment in 44 cases\n(45%) (non-CD group, 27 (61%); CD group, 17 (39%)) as EBD is not indicated. Fourteen non-CD patients had strictures due\nto malignant tumors, while 13 patients had benign strictures. Twenty-three patients (non-CD, 12; CD, 11) underwent EBD.\nForty-three EBD procedures were performed for 17 stricture sites (average: 2.5 procedures/site) in non-CD patients and 41 EBD\nprocedures for 18 stricture sites (average: 2.3 procedures/site) in CD patients. The short-term success rate was 100% (23/23),\nwhereas the long-term success rate was 92% (11/12) in non-CD patients and 82% (9/11) in CD patients. No significant\ndifferences in the surgery-free rate occurred between both groups. Furthermore, one adverse event, bleeding after EBD, was\nencountered in the non-CD group (8%, 1/12). Conclusion. EBD for small-bowel strictures demonstrated good clinical outcomes\nin non-CD patients.
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