Introduction: Hepatitis B Virus (HBV) and Human Immunodeficiency Virus\n(HIV) infection is a public health problem worldwide, particularly in sub-Saharan\nAfrica. Objective: to compare the epidemiological, clinical and biological characteristics\nof chronic HBV and HIV infection in blood donors at the National\nCenter for Blood Transfusion (NCBT) in Bangui. Patients and Methods:\nThis was an 8-month analytical cross-sectional study from August 10, 2011 to\nApril 9, 2012. During this study, we consecutively enrolled consenting blood\ndonors of both sexes in which the search for HBsAg and HIV infection was\ncarried out. Results: During the study period, 850 blood donors were collected.\nHBsAg was found in 142 donors (16.7%), of whom 55 blood donors (6.5%)\nwere coinfected with HIV. On the other hand, HIV serology was positive in\n77 blood donors (9.1%) including 55 co-infected (6.5%) with HBV. In order\nto better compare the risk factors, we have not included HIV-HBV coinfected\npatients. Only 795 blood donors were selected for the risk factor study. There\nwere 87 cases of HBsAg positive (10.9%) and 22 cases of HIV positive (2.8%).\nThe average age of HIV and HBV infected patients was 25.7 and 26.2 years,\nrespectively. Twelve blood donors (1.5%) over the age of 20 were HBsAg versus\n3 HIV positive blood donors (0.4%). Among blood donors over the age of 20,\n75 (9.9%) were HBsAg positive, while 19 (2.4%) were HIV positive. Men were\ninfected with HIV in 20 cases (2.5%), while those infected with HBV were 84\n(10.6%). The risk factor found during HIV infection and HBV was unprotected\nsex with a p of 0.0038 and 0.0017 respectively. Conclusion: The prevalence\nof HBV infection is higher than that of HIV among blood donors in\nBangui. The setting up of a national viral hepatitis control program, which will\ndevelop screening, treatment and vaccination actions could make the curve\nbend.
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