Several five membered aromatic systems having three heteroatoms at symmetrical positions such as thiadiazoles\nhave been studied for their interesting pharmacological activities. This review article covers the most active thiadiazole\nderivatives that have shown considerable biological actions such as anti-inflammatory, antimicrobial, anticonvulsant,\nanticancer. This review also discusses the structure-activity relationship of the most potent compounds. It can act as an\nimportant tool for medicinal chemists to develop newer compounds possessing thiadiazole moiety that could be better agents in\nterms of efficacy and safety.
Loading....