In this work, we have synthesized thirteen (SB1-SB13) Schiff bases derived from condensation reaction of pyrrole-2-carboxaldehyde with different aniline derivatives. The structures of the synthesized products were confirmed by physicochemical and spectral (IR and 1H NMR) means. These compounds were screened for their antimicrobial activity against five bacterial and two fungal strains and their activity was compared with standard drugs ciprofloxacin and fluconazole respectively. Among all the synthesized derivatives, SB7 was found to be more active compared to the other synthesized derivatives but less than the standard drugs.
Loading....