Diabetic foot ulcerations are historically difficult to treat despite advanced therapeutic modalities. There are numerous modalities\ndescribed in the literature ranging from noninvasive topical wound care to more invasive surgical procedures such as primary\nclosure, skin flaps, and skin grafting. While skin grafting provides faster time to closure with a single treatment compared to\ntraditional topical wound treatments, the potential risks of donor site morbidity and poor wound healing unique to the diabetic\nstate have been cited as a contraindication to its widespread use. In order to garner clarity on this issue, a literature review was\nundertaken on the use of split-thickness skin grafts on diabetic foot ulcers. Search of electronic databases yielded four studies that\nreported split-thickness skin grafts as definitive means of closure. In addition, several other studies employed split-thickness skin\ngrafts as an adjunct to a treatment that was only partially successful or used to fill in the donor site of another plastic surgery\ntechnique.When used as the primary closure on optimized diabetic foot ulcerations, split-thickness skin grafts are 78% successful\nat closing 90% of the wound by eight weeks.
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