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Inventi Impact: Transplantation

Articles

  • Inventi:htp/21764/17
    Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay,\nand Short-Term Survival after Liver Transplantation in a High MELD Population
    01-Jan-1970 Research 2017 : January - March
    Mark R Pedersen, Myunghan Choi, Jeffrey A Brink, Anil B Seetharam

    Changes in distribution policies have increased median MELD at transplant with recipients requiring increasing intensive care\nperioperatively. We aimed to evaluate association of preoperative variables with postoperative respiratory failure (PRF)/increased\nintensive care unit length of stay (ICU LOS)/short-term survival in a high MELD cohort undergoing liver transplant (LT).\nRetrospective analysis identified cases of PRF and increased ICU LOS with recipient, donor, and surgical variables examined.\nVariables were entered into regression with end points of PRF and ICU LOS > 3 days. 164 recipients were examined: 41 (25.0%)\nexperienced PRF and 74 (45.1%) prolonged ICULOS. Significant predictors of PRF with univariate analysis: BMI > 30, pretransplant\nMELD, preoperative respiratory failure, LVEF < 50%, FVC < 80%, intraoperative transfusion > 6 units, warm ischemic time >\n4 minutes, and cold ischemic time > 240 minutes. On multivariate analysis, only pretransplant MELD predicted PRF (OR 1.14,\n

    How to Cite this Article
    CC Compliant Citation: Mark R. Pedersen, Myunghan Choi, Jeffrey A.\nBrink, and Anil B. Seetharam, â??Pretransplant Factors and\nAssociations with Postoperative Respiratory Failure, ICU Length of\nStay, and Short-Term Survival after Liver Transplantation in a High\nMELD Population,â? Journal of Transplantation, vol. 2016, Article ID\n6787854, 6 pages, 2016. doi:10.1155/2016/6787854, https://\ncreativecommons.org/licenses/by/4.0/.
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