Background: Lung transplantation (LTx) is limited by the shortage of suitable donors. To overcome this problem,\nmany programs have begun to use donors with extended criteria (marginal donors). However, brain-dead patients\nwith implanted mechanical circulatory support system have rarely been considered as potential lung donors. This\ncase demonstrates the feasibility of lung transplantations from organ donors supported by a mechanical circulatory\nsupport system despite the possible difficulties of lung retrieval.\nCase presentation: Our case presents a successful procurement and bilateral lung transplantation from a donor\nsupported by a left ventricular assist device (LVAD) who experienced an intraoperatively haemodynamic complication.\nThe use of portable normothermic perfusion device let us to reduce ischemic injury and assess these marginal donor\nlungs helping us to determine the clinical suitability for transplantation. Given our extensive experience with the device\ninstrumentation and management, the EVLP process was uneventful with excellent post-transplant course.\nConclusions: This case report demonstrates the feasibility of lung transplantations from organ donors supported by a\nmechanical circulatory support system using the portable normothermic perfusion platform to assess and preserve\nthese donor lungs.
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