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Inventi Impact: Transplantation

Articles

  • Inventi:htp/31650/20
    Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and After Renal Transplantation
    Research 2020 : July - September
    Hjordis Thorsteinsdottir, Cathrin Lytomt Salvador, Geir Mjøen, Anine Lie, Meryam Sugulle, Camilla Tøndel, Atle Brun, Runar Almaas, Anna Bjerre

    Growth differentiation factor 15 (GDF-15) is strongly associated with cardiovascular disease (CVD). The aim of our study was to\nevaluate plasma and urinary levels of GDF-15 after pediatric renal transplantation (Rtx) and in children with chronic kidney\ndisease (CKD) and its associations to cardiovascular risk factors. In this cross-sectional study, GDF-15 was measured in plasma\nand urine from 53 children with a renal transplant and 83 children with CKD and related to cardiovascular risk factors\n(hypertension, obesity, and cholesterol) and kidney function. Forty healthy children served as a control group. Plasma levels of\nGDF-15 (median and range) for a Tx (transplantation) cohort, CKD cohort, and healthy controls were, respectively, 865 ng/L\n(463-3039 ng/L), 508 ng/L (183-3279 ng/L), and 390 ng/L (306-657 ng/L). The CKD and Tx cohorts both had significantly\nhigher GDF-15 levels than the control group.....................

    How to Cite this Article
    Attribution/ CC Compliant Citation: Thorsteinsdottir, Hjordis, et al. \"Growth Differentiation Factor 15 in Children with Chronic Kidney\nDisease and after Renal Transplantation.\" Disease Markers 2020 (2020).\nhttps://doi.org/10.1155/2020/6162892\nhttp://creativecommons.org/licenses/by/4.0/\n\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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