­
­
­
­

Inventi Impact: Pathology

Articles

  • Inventi:hmd/19227/16
    Morphofunctional Characteristics of Pulmonary Surfactant System and Its Effect on Immune Cells in\nInfluenza A (H1N1) Pathogenesis
    01-Jan-1970 Research 2016 : April - June
    A V Kovner, O V Potapova, V A Shkurupy, A M Shestopalov

    There is an annual increase of influenza-related SARI cases in winter months. Despite the high relevance\nof this problem, influenza pathogenesis and the role of surfactant system and its SP-A\n(surfactant protein A) enzyme in antiviral defense remain poorly understood. SP-A activates macrophage\nM1 polarization and triggers an antiviral response due to the activation of T-cells and\ndendritic cells. Therefore, surfactant system is an important element of infection protection and a\npromising therapeutic target.

    How to Cite this Article
    CC Compliant Citation: Kovner, A.V., Potapova, O.V., Shkurupy, V.A. and Shestopalov, A.M. (2016) Morphofunctional\nCharacteristics of Pulmonary Surfactant System and Its Effect on Immune Cells in Influenza A (H1N1) Pathogenesis. Open\nJournal of Pathology, 5, 1-7. http://dx.doi.org/10.4236/ojpathology.2016.61001, http://creativecommons.org/licenses/\nby/4.0/.
    Download Full Text