Background: Basal cell carcinoma (BCC) is a frequently diagnosed skin cancer\nwith variable histopathological types. BCC was not widely studied in Sudan as\nit is in the Caucasian population. Objectives: To appraise the clinical and histopathological\naspects of BCC of the skin in Sudan. Materials and methods: A\nretrospective descriptive analysis of 84 histologically diagnosed BCC specimens\nseen at three hospitals in four-year duration were reviewed and classified\ninto histological variants according to the WHO classification 2006. Data\nwere analyzed using Statistical Package for the Social Sciences, version 23.0.\nResults: The mean age (�±SD) of the study participants was 56 (�±1.75) years,\nranging from 20 to 92 years and 63.1% were females (Female to male ratio\n1.7:1). The most common incidence was among the age group 51 - 60 years.\nThe face was the primary tumor site in 89.3% with a predilection for the nasal\narea (31% of those in the face), followed by the trunk (6%). Out of the total,\n54.8% were histologically categorized as nodular/solid, while infiltrative accounts\nfor 11.9% followed by the superficial type (8.3%). Surgical margins\nwere involved in 34.5% of cases and peri-neural invasion was seen in 3.6% of\ncases, mostly were of the infiltrative variant. Conclusion: BCC in Sudan is\ncommonly present in the head as solid nodular histopathological variant\nwhich is correlated with worldwide distribution but has slightly younger age\nand female predominance; thus further studies are needed to assess risk factors\nin Sudanese patients and improve approaches for earlier diagnosis and\nbetter management.
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