The human ocular surface (front surface of the eye) is formed by two different types of epithelia: the corneal epithelium centrally\nand the conjunctival epithelium that surrounds this. These two epithelia are maintained by different stem cell populations (limbal\nstem cells for the corneal epithelium and the conjunctival epithelial stem cells). In this review, we provide an update on our\nunderstanding of these epithelia and their stem cells systems, including embryology, new markers, and controversy around the\nlocation of these stem cells. We also provide an update on the translation of this understanding into clinical applications for the\ntreatment of debilitating ocular surface diseases
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