Background: EEG is one of the most sensitive instrumental techniques for\nidentifying sepsis-related neurological complications and a valuable tool in\nthe ICU when clinical assessment is difficult. Aim of the Study: To detect\nEEG changes in neonates with evidence of sepsis. Patients and Methods:\nThis was a prospective observational study for detecting EEG changes in cases\nof proven neonatal sepsis. This study was conducted at the NICU of Al Zahraa\nUniversity Hospital for a period from October 2019 to March 2020. Our\nstudied neonates were 50. This study included full-term newborns (37 to 42\nweeks of gestational age) with clinical and laboratory evidence of sepsis (early\nand late onset). Neonatal birth asphyxia, jaundice, congenital malformations,\nsuspected inborn error of metabolism and neonates electrolytes disturbances\nwere excluded from the study. We record EEG changes during 20 min By an\nelectroencephalogram (EEG) with abioelectric amplifier (Deltamed, Bourgogne),\n(Philips) Screen. Results: Among our studied neonates (neonates\nwith evidence sepsis), 44.0% developed clinical seizures, 81% of the seizures\ngroup had abnormal EEG, 35.7% of No seizures group had abnormal EEG.\nAmong our studied neonates, 56% had abnormal EEG EEG abnormalities\nwere as follow, 26%/ had low voltage, 30% had spikes, 22% had sharp waves.\nConclusion: About 35% (one third) of neonates who didnâ??t develop clinical\nseizures had abnormal EEG, suggesting a poor correlation between clinical\nand electroencephalographic detection of seizures.
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