Fast dissolving film of domperidone was prepared by solvent casting method using super disintegrating agent. The orofilm were evaluated by some physiochemical parameters like weight variation, thickness, tensile strength, folding endurance, drug content, disintegrating and dissolution parameters. The orofilm were disintegrated at 12 seconds and having good dissolution behavior. From these concluded that domperidone orofilm have suitable for prevent quick vomiting.
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