Psoriasis is a chronic inflammatory dermatitis disease that manifests on the skin, affecting 2-3% of the population. Many treatments are available, none is universally safe and effective. Therefore, there is need to prepare polyherbal formulations to provide safe and effective treatment with lesser side effects. The present study was conducted to assess the efficacy and safety of poly herbal formulations, Psoriasis Tablet and Oil, in patients with mild to moderate psoriasis. This was 3 months, open-labeled study of psoriasis tablets and oil in 20 patients suffering from mild to moderate psoriasis. Patients received 2 tablets thrice daily for 3 months and Oil to be applied over the affected area twice daily for 3 months. The efficacy was evaluated on the basis of parameters of psoriasis area severity index (PASI) and physician’s and patient’s global evaluation at follow- up visits. Twenty patients completed the study with reduction in symptoms of psoriasis to varying degrees. At end of month 1, 2 and 3, mean score of itching had a reduction 30.43, 58.69 and 80.43% and mean score of erythema had a fall of 25, 63.33 and 81.66% and mean score of scaling had a fall of 28.57, 67.85 and 83.93% and mean score of thickness had a fall of 28.79, 53.03 and 65.15% respectively. Global assessment by the physicians and patients indicated slight to cleared response. This study confirms the efficacy and safety of psoriasis tablets and oil in Indian patients with mild to moderate psoriasis.
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