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Inventi Impact: Clinical Research

Articles

  • Inventi:pcr/26051/18
    Primary Vulvar Ewing Sarcoma in a 30-Year-Old Woman: A Case Report
    01-Jan-1970 Research 2018 : July - September
    Fatoumata Matokoma Sidibe, Hajar Ouahbi, Rajae Kanab, Layla Tahiri, Fatim Zhara El Mrabet, Samia Arifi, Hind El Fatemi, Nawfel Mellas

    Primary Ewing sarcoma (ES) and primitive neuroectodermal tumor (PNET)\nare considered as Ewing sarcoma family of tumors (ESFT), characterized by\nchromosomal translocation t(11; 22) (q24; q12) leading to a chimeric transcript\nEWS-FLI1 in 85% of cases. It typically involves the soft tissues of the\nchest wall, pelvis, paravertebral region, abdominal wall, retroperitoneal region\nand extremities in children, adolescents and young adults. It rarely occurs in\nthe female genital tract. We report an extremely rare case of advanced vulvar\nEwing sarcoma/PNET of the vulva confirmed by Fluorescence In Situ Hybridization\n(FISH) in a 30-year-old woman. The patient was treated by 6 cycles\nof chemotherapy followed by radiotherapy with favourable outcome.

    How to Cite this Article
    Sidibe, F.M., Ouahbi, H., Kanab, R., Tahiri, L., El Mrabet, F.Z., Arifi, S., El Fatemi, H. and\nMellas, N. (2018) Primary Vulvar Ewing Sarcoma in a 30-Year-Old Woman: A Case Report. Case Reports in Clinical\nMedicine, 7, 241-248, DOI: 10.4236/crcm.2018.73022, https://creativecommons.org/licenses/by/4.0/.
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