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Inventi Impact: Clinical Research

Articles

  • Inventi:pcr/29980/19
    Outcomes of Cardiac Contractility Modulation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
    Research 2019 : October - December
    Ramy Mando, Akshay Goel, Fuad Habash, Marwan Saad, Karam Ayoub, Srikanth Vallurupalli, Waddah Maskoun

    Background. Cardiac contractilitymodulation (CCM) is a device therapy for systolic heart failure (HF) in patientswith narrowQRS.\nWe aimed to perform an updated meta-analysis of the randomized clinical trials (RCTs) to assess the efficacy and safety of CCM\ntherapy. Methods. We conducted a systematic review and meta-analysis of randomized clinical trials (RCTs) between January 2001\nand June 2018. Outcomes of interest were peak oxygen consumption (peak VO2), 6-MinuteWalk Distance (6MWD), Minnesota\nLiving with Heart Failure Questionnaire (MLHFQ), HF hospitalizations, cardiac arrhythmias, pacemaker/ICD malfunctioning,\nall-cause hospitalizations, and mortality. Data were expressed as standardized mean difference (SMD) or odds ratio (OR). Results.\nFour RCTs including 801 patients (CCMn = 394) were available for analysis...................

    How to Cite this Article
    Attribution/ CC Compliant Citation: Mando, Ramy, et al. \"Outcomes of Cardiac Contractility Modulation: A Systematic Review and\nMeta-Analysis of Randomized Clinical Trials.\" Cardiovascular Therapeutics 2019 (2019).\nhttps://doi.org/10.1155/2019/9769724\nhttp://creativecommons.org/licenses/by/4.0/\n\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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