The hospital-based study was performed to investigate the prevalence of HBV and HCV infection among the adults of the Garhwali population suffering from liver complications which may provide the most recent data for planning and monitoring of health in relation with hepatitis infection in hilly Garhwal region of India was performed between June 2009 and June 2012. The result showed that, out of 5436 individuals, HBsAg positivity rate was 2.097 % and anti-HCV positivity rate was 1.968 %. Among HBsAg positive individual 62.28 % were males and 37.72 % were females. The prevalence of HBsAg positivity was highest in Tehri Garhwal district (28.07 %) and lowest in Uttarkashi district (11.40 %). Among anti-HCV positive individual 57.94 % were males and 46.06 % were females. The prevalence of anti-HCV positivity was highest in Rudra Prayag district (25.23 %) and lowest in Pauri Garhwal district (14.95 %).
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