The hospital-based study was performed to investigate the prevalence of hepatitis A virus (HAV) infection among the adult Garhwali population suffering from chronic liver disease which may provide the most updated data regarding prevalence of hepatitis A virus infection in the population of hilly Garhwal section of Uttrakhand in India was performed between May, 2011 and May, 2012. Serum analysis revealed that out of 142 individuals 52.816% are found positive. Among them 45.33% were males and 54.67% were females the percentage of HAV positivity is highest in Uttarkashi district and lowest in Rudra Prayag district. The frequency of HAV positivity is observed higher in Uttarkashi and Chamoli district and lesser in Rudra Prayag and Tehri Garhwal among both sexes in the study subjects. The prevalence of presence of HAV positive male among the total male population was 49.27% while among the female was 56.16% among the total female population. The study mostly revealed that prevalence of HAV positivity is higher in females as compared to the males.
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