To document the frequency of ABO and Rhesus blood groups in mid Karnataka region and to compare it with reports of previous studies. Design: Observational cross sectional study. Settings: Blood transfusion center at Davanagere, Karnataka. Materials & Methods: The data of blood donors from July 2009 to December 2009. Observation: Total number of donors studied was 3048. Present study showed more number prevalence of O blood group in 37.87% followed by B in 29.98%, A in 23.88% and AB in 8.29%. While 95.41% donors were Rh +ve & 4.59% were Rh –ve. The maximum donors were between in age group 20-39 years. Conclusion: O’ Blood group has number subjects compare to ABO blood groups and 95.41% are Rh +ve in this area.
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