Green tea and hibiscus are widely consumed as traditional beverages in Yemen and some regional countries. They are relatively\ncheap and the belief is that they improve health state and cure many diseases. The aim of this study was to evaluate the potential\nprotective and antibacterial activity of these two famous plants in vitro through measuring their antibacterial activity and in vivo\nthrough measuring nonenzymatic kidney markers dysfunction after induction of nephrotoxicity by gentamicin. Gram positive\nbacteria like MRSA (methicillin resistant Staphylococcus aureus) were isolated from hospitalized patientsâ�� different sources (pus\nand wound) and Gram negative bacteria including E. coli and P. aeruginosa were used in vitro study. In addition, the efficacy of\nthese plants was assessed in vivo through measuring nonenzymatic kidney markers including S. creatinine and S. urea. Green tea\nwas shown antimicrobial activity against MRSA with inhibition zone 19.67 �± 0.33mm and MIC 1.25 �± 0.00mg/mL compared with\nstandard reference (vancomycin) 18.00 �± 0.00mg/mL.Hibiscus did not exhibit a similar effect. BothHibiscus- and green tea-treated\ngroups had nephroprotective effects as they reduced the elevation in nonenzymatic kidney markers. We conclude that green tea\nhas dual effects: antimicrobial and nephroprotective.
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