Pteris vittata L. a lithophytic pteridophyte is evaluated for its antihyperglycemic activity on alloxan induced Sprague Dawley rats. Diabetes has emerged to be a major health problem with high frequency in the present population of the world, with myriads of chronic complications which results in the prominence of finding alternative drugs that have insulinotropic effect with minimum detrimental side effects. In the present study two extracts obtained from polar solvents viz. aqueous and ethanolic is studied which showed almost 77% and 72% decrease in the plasma glucose levels respectively in the experimental animal at an interval of 21 days. The effects of the extracts on lipid profile, kidney functioning and liver glycogen is also assessed which further supported Pteris vittata L. to possess potent hypoglycemic potential without any detrimental side effects on vital organs.
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