This article aims to provide detailed information on Malaysian plants used for treating inflammation. An extensive search on\nelectronic databases including PubMed, Google Scholar, Scopus, and ScienceDirect and conference papers was done to find\nrelevant articles on anti-inflammatory activity of Malaysian medicinal plants. The keyword search terms used were â??inflammation,â?\nâ??Malaysia,â? â??medicinal plants,â? â??mechanisms,â? â??in vitro,â? and â??in vivo.â? As a result, 96 articles on anti-inflammatory\nactivity of Malaysian medicinal plants were found and further reviewed. Forty-six (46) plants (in vitro) and 30 plants (in vivo) have\nbeen identified to possess anti-inflammatory activity where two plants, Melicope ptelefolia (Tenggek burung) and Portulaca\noleracea (Gelang pasir), were reported to have the strongest anti-inflammatory activity of more than 90% at a concentration of\n250 ... It was showed that the activity was mainly due to the occurrence of diverse naturally occurring phytochemicals from\ndiverse groups such as flavonoids, coumarins, alkaloids, steroids, benzophenone, triterpenoids, curcuminoids, and cinnamic acid.\nHence, this current review is a detailed discussion on the potential of Malaysian medicinal plants as an anti-inflammatory agent\nfrom the previous studies. However, further investigation on the possible underlying mechanisms and isolation of active\ncompounds still remains to be investigated.
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