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Inventi Impact: Gene Medicines

Articles

  • Inventi:pgm/31397/20
    Identification of a Novel ACTN4 Gene Mutation Which Is Resistant to Primary Nephrotic Syndrome Therapy
    Research 2020 : April - June
    Lingzhang Meng, Shan Cao, Na Lin, Jingjie Zhao, Xulong Cai, Yonghua Liang, Ken Huang, Mali Lin, Xiajing Chen, Dongming Li, Junli Wang, Lijuan Yang, Aibo Wei, Genliang Li, Qingmei Lu, Yuxiu Guo, Qiuju Wei, Junhua Tan, Meiying Huang, Yuming Huang, Jie Wang, Yunguang Liu

    ACTN4, a gene which codes for the protein alpha-actinin-4, is critical for the maintenance of the renal filtration barrier. It is well\nknown that ACTN4 mutations can lead to kidney dysfunction, such as familial focal segmental glomerulosclerosis (FSGS), a\ncommon cause of primary nephrotic syndrome (PNS). ...............................

    How to Cite this Article
    Attribution/ CC Compliant Citation: Meng, Lingzhang, et al. \"Identification of a Novel ACTN4 Gene Mutation Which Is Resistant to\nPrimary Nephrotic Syndrome Therapy.\" BioMed Research International 2019 (2019).\nhttps://doi.org/10.1155/2019/5949485\nhttp://creativecommons.org/licenses/by/4.0/\n\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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