Dental film can be a better option for sustained release of drug for local drug delivery in case of periodontitis as higher concentration of drug can be released at the intended site with reduction in side effects. Evaluation of formulation by in-vitro study was done by kill kinetics. The study was to perform in-vitro study by kill kinetics of chitosan dental film containing tobramycin. In-vitro drug release was done by kill kinetics which was carried out on Staphylococcus aureus ATCC No. 29737 and Streptococcus mutans ATCC NO. 25175. Kill kinetics study showed a sustained release of drug from the film for up to 7 days on Staphylococcus aureus and Streptococcus mutans.
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