Single antimicrobial therapy has been unable to resist the global spread of bacterial resistance. Literatures of available in vitro and\nin vivo studies were reviewed and the results showed that low frequency ultrasound (LFU) has a promising synergistic bactericidal\neffect with antibiotics against both planktonic and biofilm bacteria. It also can facilitate the release of antibiotics from medical\nimplants. As a noninvasive and targeted therapy, LFU has great potential in treating bacterial infections. However, more in-depth\nand detailed studies are still needed before LFU is officially applied as a combination therapy in the field of anti-infective treatment.
Loading....